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Folia Medica 64(5):762-769 DOI: 10.3897/folmed.64.e65507 Original Article Uric Acid Effects on Glutathione Metabolism Estimated by Induction of Glutamate- Cysteine Ligase, Glutathione Reductase, and Glutathione Synthetase in Mouse J744A.1 Macrophage Cell Line Deyana Vankova1, Yoana Kiselova-Kaneva1, Diana Ivanova1 1 Department of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, Varna, Bulgaria Corresponding author: Deyana G

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The prolonged study duration is a result of VPA poisoning rarity but similarly to the elevated prevalence of co-ingestions, may have introduced confounding factors